Publications
Amplify
A self-amplifying RNA vaccine prevents enterovirus D68 infection and disease in preclinical models – Science Translational Medicine
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A localizing nanocarrier formulation enables multi-target immune responses to multivalent replicating RNA with limited systemic inflammation
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A replicon RNA vaccine can induce durable protective immunity from SARS-CoV-2 in nonhuman primates after neutralizing antibodies have waned – PLOS Pathogens
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Evaluation of repRNA vaccine for induction and in utero transfer of maternal antibodies in a pregnant rabbit model – Molecular Therapy
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Immunogenicity and protection against Mycobacterium avium with a heterologous RNA prime and protein boost vaccine regimen — Tuberculosis
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Activate
Suppression of hepatitis B virus through therapeutic activation of RIG-I and IRF3 signaling in hepatocytes — PubMed (nih.gov)
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Spatiotemporal dynamics of innate immune signaling via RIG-I-like receptors — PubMed (nih.gov)
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Beyond sensing: Retinoic acid inducible gene-I (RIG-I) continues to expand its antiviral effector functions — PubMed (nih.gov)
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Access
Translational development of a tumor junction opening technology — Scientific Reports
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Structure-based Design of JOC-x, a Conjugatable Tumor Tight Junction Opener to Enhance Cancer Therapy
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Epithelial Junction Opener Improves Oncolytic Adenovirus Therapy in Mouse Tumor Models — nih.gov
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