Pipeline

Pioneering Impact

HDT Bio is dedicated to making a significant impact in the field of RNA vaccines by continually advancing RNA technology and constantly exploring new avenues for innovation.

Platform Flexibility

With LION™’s unique ability to deliver genetic material and other molecules to cells for various disease states, HDT Bio is well-positioned to address additional indications expanding the possibilities for personalized medicine and disease prevention.

Continuous Innovation

Through constant innovation and by demonstrating the versatility and flexibility of the LION™ platform in various disease indications, HDT Bio is capitalizing on the immense market potential and establishing itself as a dynamic company dedicated to transforming healthcare.

Infectious Diseases

HDT Bio’s COVID-19 vaccine, HDT-301, is in Phase 1 clinical trial in the US. Other COVID-19 vaccines developed using HDT Bio’s AMPLIFY platform have been authorized for use in India (GEMCOVAC-19) and are currently being studied in clinical trials in Brazil (VACCINE RNA MCTI CIMATEC HDT) and South Korea (QTP104). Beyond COVID-19, we are developing vaccines to target numerous life-threatening infectious diseases, including shingles, HIV, tuberculosis, Crimean-Congo hemorrhagic fever virus [CCHFV] (HDT-321) and Nipah virus [NiV] (HDT-331).

Product (indication)
Discovery
Lead ID
IND-enabling
Phase 1
Phase 2
Phase 3
HDT-301: COVID-19
 
HDT-201: Respiratory ID
 
HDT-321: CCHF
 
HDT-331: Nipah
 

Oncology

Because HDT Bio’s technology platform enables localized, T cell-mediated immunological memory responses, LION™ has the potential to treat or prevent cancer. The company is currently developing vaccines targeting antigens associated with pancreatic, colon, prostate, breast, and other cancers.

Product (indication)
Discovery
Lead ID
IND-enabling
Phase 1
Phase 2
Phase 3
HDT-521 (prostate cancer)
 
HDT-501 (breast cancer)
 
HDT-511 (pancreatic cancer)
 
HDT-211 (glioblastoma)