News & Publications
Press Releases
HDT Bio to Present Novel Vaccine Technologies for Cancer Immunoprevention at SITC 2023 Annual Meeting
SEATTLE, Oct. 31, 2023 /PRNewswire/ -- HDT Bio Corp., a clinical-stage private company developing advanced RNA products to treat and prevent infectious diseases and cancer, today announced that Dr. Steven Reed, Chief Executive Officer of HDT Bio, will present at the...
HDT Bio Receives $1 Million Award from BLUE KNIGHT™ Resident QuickFire Challenge in Support of Project NextGen
Award will fund the development of HDT-201, HDT Bio's thermo-stable and broad-spectrum intranasal RIG-I Agonist RNA SARS-CoV-2 antiviral candidate HDT-201 investigated as pre-exposure or post exposure prophylactic in high-risk situations SEATTLE, Oct. 4, 2023...
HDT Bio Announces Appointment of Key Clinical Oncology Experts
Scientific Advisors to provide expertise and counsel on the clinical development of its RNA-based oncology pipeline candidates HDT Bio announces esteemed medical experts Dr. Charles Cobbs of the Swedish Neuroscience Institute and Dr. Elizabeth Jaffee of Johns Hopkins...
HDT Bio Publishes Peer-Reviewed Study Demonstrating Advantages of repRNA and LION™ Technology
LION™-formulated repRNA vaccination exhibited a significant safety profile, along with enhanced efficacy and biodistribution response when compared to lipid nanoparticle (LNP)-formulated repRNA vaccines in mice Study findings, published in the peer-reviewed...
HDT Bio Publishes Peer-Reviewed Preclinical Study Demonstrating Robust Immunological Response in Mothers and Newborns Following repRNA/LION™ Vaccination
LION-formulated, repRNA vaccination against HIV-1 and ZIKV successfully produced a robust immunological response in pregnant rabbits; maternal antibodies were transferred in utero to newborn kits Findings published in the peer-reviewed journal Molecular Therapy...
Publications
An RNA-Based Vaccine Platform for Use against Mycobacterium tuberculosis – Vaccines 2023
Click here to view article
Replicating RNA platform enables rapid response to the SARS-CoV-2 Omicron variant and elicits enhanced protection in naïve hamsters compared to ancestral vaccine. — EBioMedicine
Click here to view article
A replicon RNA vaccine induces durable protective immunity from SARS-CoV-2 in nonhuman primates after neutralizing antibodies have waned — BiorXiv
Click here to view article
Replicating RNA vaccination elicits an unexpected immune response that efficiently protects mice against lethal Crimean-Congo hemorrhagic fever virus challenge. — EBioMedicine
Click here to view article
Intramuscular delivery of formulated RNA encoding six linked nanobodies is highly protective for exposures to three Botulinum neurotoxin serotypes. — Nature Scientific Reports
Click here to view article
HDT in the News
Bioprocess Online: Why Therapeutic Cancer Vaccines Haven’t Worked To Date
Click here to view article
Bioprocess Online Live: Why The Cancer Vaccine Concept Is En Vogue Again
Click here to view article
Bioprocess Online: Why The Cancer Vaccine Concept Is En Vogue Again
Click here to view article
Law360: Indian Pharma Co. Can’t Get Fees In $950M COVID Vax Suit
Click here to view article
Bioprocess Online Live: Where Therapeutic Cancer Vaccines Go Next
Click here to view article